Using the soluble antigen of Anaplasma marginale to sensitizing the latex by chemical cross-link, a latex agglutination test ( LAT) was developed for detecting serum antibody to A. marginale. 利用边缘无形体可溶性抗原,以化学交联的方式致敏羧化胶乳制成胶乳抗原,成功地建立了一种检测牛边缘无形体血清抗体的胶乳凝集试验(LAT)诊断方法。